What is mesothelioma? Pleural mesothelioma & Peritoneal mesothelioma? What causes mesothelioma?

What is mesothelioma?
Mesothelioma is a cancer that initiates from mesothelial cells. The cells line the outer part of most of the body’s organs, forming a protective layer of membrane called the mesothelium.
It forms a mass layer or tumour and others grow along with the mesothelium and form a thick layer of covering. In later stages, mesothelioma may spread (metastasise) to other parts of the body.

Pleural mesothelioma
This type of mesothelium is that it covers lungs. The one that develops in the pleura is known as malignant pleural mesothelioma or, basically, pleural mesothelioma. It accounts for more than 90% of all mesotheliomas. Though pleural mesothelioma involves the lungs lining, this is not lung cancer and is treated in a different way.


There are mainly 2 layers in pleura. The innermost layer lines the lung surface and is known as visceral pleura. The outer layer lines the chest wall and the diaphragm, and is called the parietal pleura.

pleural cavity (also called the pleural space) lies between the 2 layers, which contains a small portion of fluid. The fluid allows the 2 layers of pleura to cover over each other so the lungs move smoothly against the chest wall when you breathe.

When the disease develops in the pleura, the fragile layers thicken and may put pressure on the lung, preventing it from expanding when Inhaling. On breathing some fluid often collects between the 2 layers i.e. called a pleural effusion.

Peritoneal mesothelioma
The mesothelium that covers the walls & organs of the abdomen and pelvis is known as the peritoneum. Mesothelioma that develops inside the peritoneum is called as malignant peritoneal mesothelioma or peritoneal mesothelioma.

The peritoneum
The peritoneum has two layers. The innermost layer covers the surface of organs such as the bowel, liver & ovaries & is knows as the visceral peritoneum. The outer layer covers abdomen and pelvis walls & called as parietal peritoneum. In between the 2 layers, We have the peritoneal cavity, which normally contains the fluid. This fluid allows the 2 layers to cover over each other as you move around. People suffering from peritoneal mesothelioma, excess fluid often collects between the 2 layers known as ascites or peritoneal effusion.

What causes mesothelioma?
A: Exposure to asbestos is the main cause of mesothelioma. Very rarely, mesothelioma has been linked with previous radiotherapy to the chest.

It was used in numerous building construction from the 1940s until 1987. Since 2004, Australia has had a ban on asbestos being sold, reused and/or imported. It is still present
in many older buildings, so special precautions must be taken when renovating or  demolishing. It has also been found in some recently imported products despite the ban.
People most likely to have been exposed to asbestos at work include asbestos miners and millers, asbestos cement manufacturing workers, laggers and insulators, builders, plumbers and electricians, automotive industry workers, mechanics, transport workers (especially waterside workers), and textile workers. People who doesn’t have direct contact with asbestos but are indirectly exposed to it can also develop mesothelioma.It includes people cleaning work clothes with asbestos fibres etc.

It may take years for mesothelioma to develop after the person is exposed to asbestos material. It may be between 20 and 60 years after exposure.


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